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Tissue Regeneration - From Basic Biology to Clinical Appln. by J. Davies

By J. Davies

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Biophysical stimuli on cells during tissue differentiation at implant interfaces. J Biomech, Vol. 30, No. 6, pp. , & Bissell, M. (1994). Extracellular matrix-dependent tissuespecific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. Proc. Natl. Acad. Sci USA Vol. 91, pp. 12378-12382. , & Monici, M. (2010). Direct and indirect photomechanical effects in cells and tissues. Perspectives of application in biotechnology and medicine. In: Cell Mechanochemistry.

Improving muscle healing after laceration injury. Researchers at the University of Alberta have used LIPUS to gently massage teeth roots and jawbones to cause growth or regrowth, and have grown new teeth in rabbits after lower jaw surgical lengthening (Distraction osteogenesis). As of June 2006, a device has been licensed by the Food and Drug Administration (FDA) and Health Canada for use by orthopedic surgeons. It has not yet been approved by either Canadian or American regulatory bodies and a market-ready model is currently being prepared.

Effects of nitric oxide synthase inhibitors on bone formation in rats. , Vol. 21, No. 6, pp. 48790. , & Henderson, SA. (1996). Mechanical stimulation of organogenic cardiomyocyte growth in vitro. Am. J. , Vol. 270(5 Pt 1), pp. C1284-92. , & Klein-Nulend, J. (2007). Extracellular NO signalling from a mechanically stimulated osteocyte. , Vol. 40 Suppl 1, pp. S89-95. , & Klein-Nulend. (2010). Mechanobiology of bone: From cell to organ, In: Cell Mechanochemistry. , & van Loon, J, pp. 131-152, Transworld Research Network, ISBN: 978-81-7895-458-5, Kerala, India.

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