By Barkur S. Shastry (auth.), Anton A. Komar (eds.)
In contemporary years, unmarried nucleotide polymorphisms have bought elevated and particular awareness in a swiftly constructing box of customized drugs and drug therapy. Comprising greater than 80 percentage of all recognized polymorphisms, unmarried nucleotide polymorphisms (SNPs) are essentially liable for phenotypic adjustments among participants, and feature been steered to impact the advance of ailments in people and the reaction to drug remedy and environmental rigidity. In Single Nucleotide Polymorphisms: tools and Protocols, moment Edition, specialist researchers discover the most recent advances during this sector, highlighting the large development that has been made in SNP genotyping, analyzing contemporary advancements in high-throughput genotyping ways, and exploring our new figuring out of the impression of SNPs on gene functionality. Chapters deal with the impression of SNPs on phenotype, learn SNP databases, examine equipment which have been utilized for SNP bioinformatics discovery and research, and speak about complicated experimental ways used for SNP detection. Composed within the hugely winning Methods in Molecular Biology™ sequence structure, every one bankruptcy encompasses a short creation, step by step tools, a listing of helpful fabrics, and a Notes part which stocks tips about troubleshooting and keeping off recognized pitfalls.
Current and cutting edge, Single Nucleotide Polymorphisms: tools and Protocols,Second Edition is a vital guidebook for person researchers in addition to associations and corporations operating within the field.
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