By Douglas Kondziolka
The best way to steer clear of and deal with issues in stereotactic radiosurgery? the most up-tp-date and fascinating advancements in addition to crucial findings on refinements are released during this new quantity. It addresses themes similar to benign and malignant tumor radiosurgery, trigeminal neuralgia and headache, spectroscopic imaging, new checks, extracranial radiosurgery, and vascular malformations. The fine quality peer-reviewed experiences have been awarded via specialists of their box on the 2003 assembly of the overseas Stereotactic Radiosurgery Society. This booklet is of precise curiosity to neurosurgeons, radiation oncologists, scientific physicists, neurologists, and oncologists, who require designated info to maintain updated with the real advancements at the use of stereotactic radiosurgery.
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Edu Gibbs/Chang/Pham/Adler 28 Kondziolka D (ed): Radiosurgery. Basel, Karger, 2004, vol 5, pp 29–37 Construction and Verification of STI Device for Cat Model Masako N. Hosono a, Kiyoaki Tanaka b, Tomohiro Sahara a, Misao Nishikawa b, Kentarou Ishii a, Satoko Kondo a, Yoshie Takada a, Haruyuki Fukuda a, Mitsuhiro Hara b, Yuichi Inoue a Departments of aRadiology and bNeurosurgery, Osaka City University Graduate School of Medicine, Osaka, Japan Abstract In order to investigate the radiobiological effects of stereotactic irradiation (STI) on humans, the experimental STI with the similar dose to clinical practices and long-term follow-up would be essential, and the accuracy for the STI system should be well assured.
1). Target coverage ranged from 79 to 100%. The maximum dose to the spinal cord/cauda equina was determined directly based on the DVH for vertebral body and extra-axial lesions. Because all AVMs were contained within the intraspinal component, the maximum spinal cord dose to these lesions was assumed to be represented by the maximum dose delivered by the treatment plan. Complete dosimetric and volumetric data were available for 8 of 11 patients. Conformal avoidance of radiation dose spread to the spinal cord was largely achievable with vertebral body and extra-axial lesions (fig.
1% (n ϭ 95) of cases. 4%). The most common sequelae in descending frequency were headache (17), seizures (11), fluid retention and other steroid side effects (7 each) and neurologic change (7). Multivariate analysis did not show any single factor to predict for increased risk of sequelae. Conclusions: Approximately one-third of patients experience acute sequelae following radiosurgery, most of which are mild to moderate. Severe side effects are uncommon. None of the studied risk factors were predictive for increased sequelae.