By Thomas J. Anderson, William R. Miller (auth.), Robert B. Dickson, Marc E. Lippman (eds.)

The present quantity represents the fourth over a interval of 5 years in our sequence on Advances within the mobile and Molecular Biology of Breast melanoma. the 1st 3 volumes have been entitled Breast melanoma: mobile and Molecular Biology, Regulatory Mechanisms in Breast melanoma, and Genes, Oncogenes, and Hormones, respectively. all through this sequence, we have now attempted to take a vast examine state-of-the-art issues in easy technological know-how study into breast melanoma. This try out has led to quite a lot of material, together with rodent and human version structures, oncogenes, suppressor genes, development components, hormones, tumor-host interactions, and determinants of metastases. in view that our final quantity, examine in breast melanoma has endured to continue at an explosive price. we are hoping the present quantity will give you the reader with a number of the pleasure felt by means of the editors and authors as we start to appreciate this all-too-common illness. the 1st element of this publication is dedicated to the elemental strategies of proli­ feration, differentiation, and malignant development of breast melanoma. T.l. Anderson and W.R. Miller lead off with a close description of controls on proliferation within the basic human breast and in breast melanoma. This bankruptcy strongly emphasizes pathological points. the second one bankruptcy, by way of M.R. Stampfer and P. Yaswen, provides a corresponding point of view via a presentation of experiments with human mammary epithelial cells in tradition. the second one portion of the ebook emphasizes the genetic foundation for breast melanoma onset and malignant development. bankruptcy three, through M.-C. King and S.