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Is full recovery from depression possible? by Mike Briley

By Mike Briley

content material: 1. creation 2. What Constitutes restoration from melancholy three. How universal is terrible final result in melancholy: The NIMH examine; the Zurich examine; elements Affecting final result of melancholy four. Demographic features five. disorder Variables 6. remedy Variables 7. organic Correlates eight. long term remedy of melancholy nine. financial effect of Recurrent Depression

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Extra resources for Is full recovery from depression possible?

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Biological correlates Sleep disturbances A number of changes in sleep patterns occur in depressed patients (Kasper, 1997). The ratio of average delta wave counts during the first REM period to that in the second is designated the delta sleep ratio (Kasper, 1997); it has been reported to predict the likelihood of recurrence of depression. , 1990). , 1997). Patients with abnormal sleep profiles showed lower remission rates than those with normal sleep patterns but, despite this, 75% of patients with sleep disturbances experienced remission when pharmacological treatment was added to psychotherapy.

1996a), which may offer particular advantages during long-term treatment. Nefazodone is a selective inhibitor of serotonin reuptake with potent 5-HT2 receptor antagonist activity. , 1994). Mirtazapine is an antidepressant that increases noradrenergic and serotonergic neurotransmission through blockade of central ␣2-adrenergic auto- and heteroreceptors (Davis and Wilde, 1996). Remission rates during long-term treatment with this agent have been reported to be comparable with those achieved with TCAs (Davis and Wilde, 1996).

Paroxetine is better than placebo in 43 965_Depression_pages 24-9-98 10:17 am Page 44 relapse prevention and the prophylaxis of recurrent depression. Int Clin Psychopharmacol 1993; 8: 189–95. Montgomery SA, Bebbington PE, Cowen P, Deakin W, Freeling P, Hallström C et al. Guidelines for treating depressive illness with antidepressants. J Psychopharmacol 1993a; 7: 19–23. Montgomery SA, Racagini G, Coppen A, Bunney WE, Carlsson P, De Montigny C et al. Eur Neuropsychopharmacol 1993b; 3: 153–6. Montgomery SA, Kasper S.

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