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Fourier Transforms - New Analytical Approaches and FTIR by Goran S. Nikolić (editor)

By Goran S. Nikolić (editor)

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As active substance, these drugs contain CuSO4 (Expert group, 2002). In the literature is known that metal complex with polysaccharides and their derivatives are of growing importance in medicine and pharmacy. , 1998). These complexes are very stable during prolonged storage and are not toxic. Copper(II) ion is used in the treatment of microcytic hypochromic anemia. It is apsorbed from the lower part gastrointestinal tract. 6-2 mg daily). 4. Bioactive copper-pullulan complex Pullulan is a linear exopolysaccharide of α-D-glucopyranose that is often described as a α(1→6) linked polymer of maltotriose subunits.

We had to restrict ourselves to a few examples of wide potentialities of the method of FTIR spectroscopy in investigating the relationships between the structure and the properties of extracellular polysaccharides and its complexes with different metal ions. 3. Copper(II) ion and its significance Copper(II) ion is a biologically active, essential ion, creating ability and positive redox potential allow participation in biological transport reactions. Cu(II) complexes possess a wide range of biological activity and are among the most potent antiviral, antitumor and antiinflammatory agents (Vosburg & Cooper, 1941).

The carbohydrate type compounds as ligands have been of a considerable interest. Simple sugars and their derivatives with reduced and oxidized groups form metal ion complexes of a various composition and stability. , 2003). , 1976; Gyurcsik & Nagy, 2000). , 2002). The interaction of Cu(II), Ni(II) and Fe(III) ions with dextran may be used for their speciation by ultrafiltration (Solpan & Sahan, 1993). , 2007). In the section, we analyzed the IR spectra of Cu(II) ions complexes with reduced low molar dextran (RLMD).

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